Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| BRCA | rs28932170 | chr12:75884254 | C/T | 5.07E-5 | 1014 | 21.3 | 24.27 | 18.77 | KM Plot |
| BRCA | rs290795 | chr7:130415686 | A/T | 2.72E-7 | 1028 | 13.02 | 20.7 | 22.08 | KM Plot |
| BRCA | rs2909984 | chr7:71900355 | A/G | 2.98E-5 | 1028 | 21.17 | 25.77 | 17.2 | KM Plot |
| BRCA | rs2985757 | chr1:39059701 | C/T | 4.77E-11 | 1028 | 5.37 | 22.2 | 21.57 | KM Plot |
| BRCA | rs315929 | chr2:113869407 | C/T | 1.92E-8 | 1028 | 22.17 | 20.87 | 6.93 | KM Plot |
| BRCA | rs3181313 | chr19:15168621 | C/T | 3.25E-5 | 1021 | 21.48 | 23.7 | 12.37 | KM Plot |
| BRCA | rs34047458 | chr3:46253599 | C/G | 4.89E-7 | 1024 | 22.03 | 18.4 | 21.33 | KM Plot |
| BRCA | rs34073838 | chr3:46337692 | A/C | 3.21E-6 | 1026 | 22 | 18.4 | 20.4 | KM Plot |
| BRCA | rs34189825 | chr3:98602036 | CAT/C | 5.03E-7 | 1022 | 21.45 | 23.8 | 5.27 | KM Plot |
| BRCA | rs34631700 | chr20:25102481 | G/A | 2.98E-5 | 1015 | 22.17 | 22 | 14.57 | KM Plot |
| BRCA | rs35014305 | chr20:2757781 | G/A | 1.03E-5 | 1019 | 22.2 | 20.73 | 12.32 | KM Plot |
| BRCA | rs35218998 | chr3:46328715 | T/C | 3.08E-6 | 1027 | 22.03 | 18.43 | 20.4 | KM Plot |
| BRCA | rs35239102 | chr6:20533341 | T/C | 4.33E-9 | 1023 | 21.5 | 21.77 | 8.87 | KM Plot |
| BRCA | rs352543 | chr6:69181181 | A/G | 1.21E-5 | 1028 | 21.33 | 23.93 | 5.03 | KM Plot |
| BRCA | rs35258121 | chr20:30502365 | C/T | 3.82E-14 | 1020 | 21.28 | 23.8 | 8.5 | KM Plot |